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Stanford PathBench
pathology
H&E

Comprehensive benchmark evaluating 31 foundation models across 41 tasks from TCGA, CPTAC, and external datasets.

22 models evaluated
41 tasks
Organs:
lung
brain
breast
prostate
kidney
colon
rectum
bladder
skin
gi
multi-organ

Detailed Results

Model
Average
rank
Average
metric
BACH
AUROC
Bladder Histology Subtype
AUROC
Bladder mRNA Cluster
AUROC
BRACS
AUROC
Brain Expression Subtype
AUROC
Brain Histology Subtype
AUROC
Brain Necrosis
AUROC
BreakHis
AUROC
Chromatin Remodeling
AUROC
ER Status
AUROC
ERG Status
AUROC
GI Subtype
AUROC
IDH Status
AUROC
Immune Group
AUROC
Kidney Subtype
AUROC
LC25000
AUROC
Lung Expression Subtype
AUROC
Lung Grade
AUROC
Lung Histology (OOD 1)
AUROC
Lung Histology (OOD 2)
AUROC
Lung Stage
AUROC
Lung Stage (OOD)
AUROC
LUSC vs LUAD
AUROC
MGMT Status
AUROC
MGMT Status (OOD)
AUROC
MHIST
AUROC
mTOR Pathway
AUROC
MYC Activation (CPTAC)
AUROC
MYC Status
AUROC
NCT-CRC-HE
AUROC
P53 Pathway
AUROC
PAM50 Status
AUROC
PI3K Pathway
AUROC
PR Status
AUROC
Prostate mRNA Cluster
AUROC
SICAPv2
AUROC
SWI/SNF Pathway
AUROC
Tumor Grade (CPTAC)
AUROC
Tumor Grade (TCGA)
AUROC
Tumor Label
AUROC
UniToPatho
AUROC
4.900.830
0.991
[0.98-1.00]
0.703
[0.57-0.82]
0.884
[0.82-0.95]
0.939
[0.92-0.95]
0.829
[0.79-0.86]
0.845
[0.79-0.90]
0.592
[0.40-0.79]
0.984
[0.98-0.99]
0.809
[0.74-0.86]
0.903
[0.85-0.95]
0.839
[0.78-0.89]
0.748
[0.69-0.80]
0.960
[0.93-0.98]
0.888
[0.87-0.91]
0.983
[0.96-1.00]
1.000
[1.00-1.00]
0.925
[0.90-0.95]
0.738
[0.66-0.81]
0.854
[0.67-0.99]
0.848
[0.75-0.94]
0.620
[0.49-0.74]
0.475
[0.24-0.73]
0.961
[0.95-0.97]
0.695
[0.64-0.75]
0.485
[0.28-0.70]
0.941
[0.93-0.95]
0.766
[0.70-0.83]
0.845
[0.80-0.88]
0.659
[0.62-0.69]
0.997
[1.00-1.00]
0.900
[0.85-0.94]
0.820
[0.75-0.88]
0.745
[0.73-0.76]
0.777
[0.71-0.85]
0.822
[0.77-0.87]
0.955
[0.95-0.96]
0.844
[0.79-0.90]
0.805
[0.73-0.87]
0.783
[0.74-0.82]
0.996
[0.99-1.00]
0.864
[0.85-0.87]
5.070.826
0.988
[0.98-1.00]
0.701
[0.56-0.82]
0.887
[0.82-0.94]
0.931
[0.91-0.95]
0.839
[0.80-0.87]
0.830
[0.77-0.89]
0.653
[0.46-0.83]
0.974
[0.97-0.98]
0.836
[0.78-0.89]
0.912
[0.85-0.96]
0.811
[0.74-0.87]
0.735
[0.68-0.79]
0.955
[0.92-0.98]
0.885
[0.86-0.90]
0.962
[0.93-0.99]
1.000
[1.00-1.00]
0.930
[0.90-0.95]
0.734
[0.66-0.81]
0.764
[0.51-0.96]
0.854
[0.76-0.94]
0.642
[0.52-0.76]
0.446
[0.21-0.69]
0.971
[0.96-0.98]
0.693
[0.64-0.75]
0.558
[0.33-0.78]
0.892
[0.87-0.91]
0.777
[0.71-0.84]
0.863
[0.83-0.90]
0.657
[0.62-0.69]
0.997
[1.00-1.00]
0.894
[0.85-0.93]
0.806
[0.73-0.87]
0.722
[0.70-0.74]
0.760
[0.69-0.82]
0.820
[0.77-0.87]
0.940
[0.93-0.95]
0.824
[0.77-0.88]
0.818
[0.75-0.88]
0.776
[0.74-0.81]
0.996
[0.99-1.00]
0.824
[0.81-0.83]
5.460.824
0.970
[0.95-0.99]
0.689
[0.55-0.81]
0.883
[0.81-0.94]
0.911
[0.89-0.93]
0.838
[0.80-0.87]
0.843
[0.79-0.90]
0.585
[0.38-0.78]
0.974
[0.97-0.98]
0.823
[0.76-0.88]
0.930
[0.88-0.97]
0.805
[0.73-0.87]
0.717
[0.66-0.77]
0.974
[0.95-0.99]
0.891
[0.87-0.91]
0.967
[0.94-0.99]
1.000
[1.00-1.00]
0.922
[0.89-0.95]
0.741
[0.67-0.81]
0.794
[0.57-0.96]
0.849
[0.75-0.93]
0.650
[0.53-0.76]
0.407
[0.18-0.67]
0.964
[0.95-0.98]
0.669
[0.62-0.72]
0.569
[0.34-0.77]
0.892
[0.87-0.91]
0.772
[0.71-0.83]
0.868
[0.83-0.91]
0.676
[0.64-0.71]
0.998
[1.00-1.00]
0.913
[0.87-0.95]
0.786
[0.72-0.85]
0.737
[0.72-0.76]
0.787
[0.72-0.85]
0.810
[0.76-0.86]
0.935
[0.93-0.94]
0.836
[0.78-0.89]
0.830
[0.77-0.89]
0.775
[0.73-0.81]
0.995
[0.99-1.00]
0.826
[0.82-0.84]
4.950.824
0.982
[0.97-0.99]
0.716
[0.58-0.83]
0.879
[0.80-0.94]
0.937
[0.92-0.95]
0.845
[0.81-0.88]
0.857
[0.80-0.91]
0.588
[0.39-0.77]
0.966
[0.96-0.97]
0.805
[0.75-0.87]
0.910
[0.85-0.96]
0.792
[0.72-0.86]
0.734
[0.68-0.79]
0.970
[0.94-0.99]
0.886
[0.86-0.91]
0.968
[0.94-0.99]
1.000
[1.00-1.00]
0.932
[0.91-0.95]
0.715
[0.64-0.79]
0.805
[0.57-0.96]
0.856
[0.76-0.94]
0.675
[0.55-0.80]
0.434
[0.23-0.64]
0.967
[0.95-0.98]
0.699
[0.64-0.75]
0.474
[0.27-0.68]
0.892
[0.87-0.91]
0.768
[0.70-0.83]
0.863
[0.83-0.90]
0.680
[0.64-0.71]
0.998
[1.00-1.00]
0.894
[0.84-0.94]
0.826
[0.76-0.88]
0.733
[0.71-0.75]
0.787
[0.72-0.85]
0.799
[0.75-0.85]
0.936
[0.93-0.94]
0.819
[0.76-0.87]
0.786
[0.71-0.85]
0.776
[0.73-0.82]
0.997
[0.99-1.00]
0.839
[0.83-0.85]
5.880.820
0.982
[0.97-0.99]
0.725
[0.60-0.84]
0.843
[0.77-0.91]
0.913
[0.89-0.93]
0.831
[0.79-0.87]
0.819
[0.76-0.88]
0.512
[0.31-0.71]
0.977
[0.97-0.98]
0.825
[0.76-0.88]
0.915
[0.86-0.96]
0.783
[0.71-0.84]
0.712
[0.66-0.77]
0.964
[0.94-0.98]
0.896
[0.88-0.92]
0.972
[0.94-0.99]
1.000
[1.00-1.00]
0.914
[0.88-0.94]
0.685
[0.61-0.77]
0.798
[0.57-0.96]
0.832
[0.75-0.92]
0.647
[0.53-0.76]
0.475
[0.25-0.71]
0.964
[0.95-0.98]
0.710
[0.65-0.76]
0.440
[0.24-0.66]
0.903
[0.88-0.92]
0.773
[0.71-0.83]
0.858
[0.82-0.90]
0.680
[0.65-0.71]
0.996
[1.00-1.00]
0.889
[0.84-0.93]
0.788
[0.72-0.85]
0.740
[0.72-0.76]
0.795
[0.72-0.86]
0.815
[0.76-0.86]
0.956
[0.95-0.96]
0.822
[0.76-0.87]
0.828
[0.76-0.89]
0.783
[0.74-0.82]
0.994
[0.99-1.00]
0.857
[0.85-0.87]
7.150.817
0.970
[0.95-0.99]
0.700
[0.57-0.82]
0.849
[0.76-0.92]
0.910
[0.89-0.93]
0.828
[0.79-0.86]
0.835
[0.78-0.89]
0.595
[0.38-0.80]
0.956
[0.95-0.96]
0.795
[0.73-0.85]
0.908
[0.85-0.96]
0.794
[0.72-0.86]
0.745
[0.69-0.80]
0.968
[0.94-0.99]
0.882
[0.86-0.90]
0.965
[0.93-0.99]
1.000
[1.00-1.00]
0.926
[0.90-0.95]
0.715
[0.64-0.79]
0.781
[0.55-0.96]
0.851
[0.75-0.93]
0.632
[0.51-0.75]
0.398
[0.19-0.61]
0.963
[0.95-0.98]
0.704
[0.65-0.76]
0.521
[0.30-0.73]
0.884
[0.86-0.90]
0.748
[0.68-0.81]
0.842
[0.80-0.88]
0.663
[0.63-0.70]
0.998
[1.00-1.00]
0.902
[0.85-0.94]
0.819
[0.75-0.88]
0.734
[0.72-0.75]
0.775
[0.71-0.84]
0.810
[0.76-0.86]
0.924
[0.92-0.93]
0.831
[0.78-0.88]
0.800
[0.72-0.87]
0.766
[0.72-0.80]
0.996
[0.99-1.00]
0.824
[0.81-0.83]
7.930.809
0.961
[0.94-0.98]
0.704
[0.58-0.82]
0.849
[0.76-0.92]
0.911
[0.89-0.93]
0.826
[0.79-0.86]
0.833
[0.78-0.89]
0.611
[0.42-0.81]
0.962
[0.96-0.97]
0.824
[0.77-0.88]
0.863
[0.79-0.92]
0.752
[0.68-0.82]
0.697
[0.64-0.76]
0.968
[0.94-0.99]
0.882
[0.86-0.90]
0.955
[0.92-0.99]
1.000
[1.00-1.00]
0.900
[0.87-0.93]
0.689
[0.61-0.77]
0.705
[0.44-0.92]
0.850
[0.76-0.94]
0.657
[0.53-0.78]
0.333
[0.13-0.55]
0.957
[0.94-0.97]
0.704
[0.65-0.75]
0.519
[0.29-0.73]
0.896
[0.88-0.92]
0.761
[0.70-0.82]
0.834
[0.79-0.88]
0.677
[0.64-0.71]
0.998
[1.00-1.00]
0.900
[0.85-0.94]
0.789
[0.73-0.85]
0.725
[0.71-0.74]
0.778
[0.71-0.85]
0.779
[0.72-0.83]
0.932
[0.93-0.94]
0.816
[0.76-0.87]
0.814
[0.74-0.88]
0.774
[0.73-0.81]
0.995
[0.99-1.00]
0.808
[0.80-0.82]
9.610.808
0.987
[0.98-1.00]
0.709
[0.58-0.82]
0.878
[0.80-0.94]
0.917
[0.90-0.93]
0.829
[0.79-0.86]
0.882
[0.83-0.93]
0.669
[0.49-0.84]
0.959
[0.95-0.97]
0.824
[0.76-0.88]
0.860
[0.79-0.92]
0.773
[0.70-0.84]
0.704
[0.64-0.76]
0.964
[0.94-0.98]
0.848
[0.82-0.87]
0.953
[0.91-0.99]
1.000
[1.00-1.00]
0.898
[0.86-0.93]
0.704
[0.62-0.78]
0.749
[0.53-0.95]
0.813
[0.71-0.90]
0.631
[0.50-0.75]
0.360
[0.18-0.56]
0.943
[0.92-0.96]
0.672
[0.62-0.72]
0.518
[0.29-0.72]
0.908
[0.89-0.93]
0.816
[0.76-0.87]
0.823
[0.78-0.86]
0.612
[0.58-0.65]
0.995
[0.99-1.00]
0.876
[0.82-0.92]
0.780
[0.70-0.86]
0.700
[0.68-0.72]
0.724
[0.64-0.80]
0.779
[0.72-0.83]
0.912
[0.90-0.92]
0.813
[0.75-0.87]
0.801
[0.72-0.87]
0.736
[0.69-0.78]
0.995
[0.99-1.00]
0.819
[0.81-0.83]
10.120.801
0.922
[0.89-0.95]
0.644
[0.50-0.78]
0.845
[0.77-0.91]
0.884
[0.86-0.90]
0.818
[0.78-0.85]
0.807
[0.75-0.87]
0.592
[0.39-0.78]
0.969
[0.96-0.97]
0.789
[0.72-0.85]
0.918
[0.87-0.96]
0.739
[0.66-0.81]
0.690
[0.63-0.75]
0.960
[0.93-0.98]
0.876
[0.85-0.90]
0.971
[0.94-0.99]
1.000
[1.00-1.00]
0.909
[0.88-0.94]
0.679
[0.60-0.76]
0.689
[0.43-0.92]
0.843
[0.76-0.92]
0.636
[0.51-0.75]
0.390
[0.24-0.54]
0.952
[0.93-0.97]
0.699
[0.64-0.76]
0.544
[0.30-0.75]
0.806
[0.78-0.83]
0.750
[0.69-0.81]
0.828
[0.79-0.87]
0.667
[0.63-0.70]
0.997
[1.00-1.00]
0.886
[0.83-0.93]
0.763
[0.69-0.83]
0.720
[0.70-0.74]
0.772
[0.70-0.84]
0.795
[0.74-0.84]
0.927
[0.92-0.93]
0.804
[0.74-0.86]
0.770
[0.70-0.83]
0.778
[0.74-0.82]
0.989
[0.98-0.99]
0.808
[0.80-0.82]
9.950.800
0.973
[0.95-0.99]
0.682
[0.55-0.81]
0.816
[0.73-0.89]
0.928
[0.91-0.94]
0.802
[0.77-0.84]
0.800
[0.74-0.86]
0.601
[0.41-0.79]
0.951
[0.94-0.96]
0.799
[0.74-0.85]
0.868
[0.80-0.93]
0.740
[0.66-0.82]
0.681
[0.62-0.74]
0.960
[0.93-0.98]
0.873
[0.85-0.90]
0.959
[0.93-0.99]
1.000
[1.00-1.00]
0.878
[0.84-0.91]
0.671
[0.58-0.75]
0.558
[0.29-0.81]
0.857
[0.77-0.93]
0.678
[0.57-0.79]
0.550
[0.34-0.79]
0.935
[0.92-0.95]
0.711
[0.66-0.76]
0.477
[0.27-0.68]
0.890
[0.87-0.91]
0.748
[0.69-0.81]
0.841
[0.80-0.88]
0.643
[0.61-0.68]
0.998
[1.00-1.00]
0.886
[0.84-0.93]
0.775
[0.70-0.85]
0.708
[0.69-0.73]
0.722
[0.65-0.79]
0.792
[0.74-0.84]
0.944
[0.94-0.95]
0.786
[0.73-0.84]
0.751
[0.68-0.82]
0.744
[0.70-0.79]
0.984
[0.98-0.99]
0.853
[0.84-0.86]
11.850.790
0.983
[0.97-0.99]
0.638
[0.50-0.77]
0.803
[0.71-0.88]
0.932
[0.92-0.95]
0.781
[0.74-0.82]
0.812
[0.74-0.88]
0.616
[0.41-0.81]
0.952
[0.94-0.96]
0.759
[0.69-0.82]
0.826
[0.75-0.90]
0.783
[0.71-0.85]
0.689
[0.63-0.74]
0.958
[0.93-0.98]
0.860
[0.84-0.88]
0.953
[0.92-0.98]
1.000
[1.00-1.00]
0.911
[0.88-0.94]
0.696
[0.62-0.77]
0.625
[0.34-0.87]
0.819
[0.72-0.91]
0.667
[0.55-0.78]
0.603
[0.38-0.81]
0.941
[0.92-0.96]
0.665
[0.61-0.72]
0.419
[0.23-0.62]
0.850
[0.82-0.87]
0.734
[0.66-0.80]
0.809
[0.76-0.85]
0.619
[0.58-0.66]
0.998
[1.00-1.00]
0.853
[0.79-0.90]
0.741
[0.66-0.82]
0.703
[0.68-0.72]
0.710
[0.63-0.79]
0.781
[0.72-0.83]
0.935
[0.93-0.94]
0.731
[0.66-0.80]
0.725
[0.64-0.80]
0.708
[0.66-0.75]
0.988
[0.98-0.99]
0.834
[0.82-0.84]
12.710.790
0.975
[0.96-0.99]
0.642
[0.50-0.78]
0.834
[0.76-0.91]
0.902
[0.88-0.92]
0.774
[0.74-0.81]
0.806
[0.74-0.86]
0.483
[0.29-0.68]
0.923
[0.91-0.93]
0.742
[0.67-0.81]
0.909
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0.653
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0.880
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0.694
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0.993
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0.851
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0.815
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0.915
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0.945
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0.877
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0.863
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0.762
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0.743
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0.726
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0.993
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0.817
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12.460.788
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0.800
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0.925
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0.799
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0.746
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0.664
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0.954
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0.845
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0.943
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0.598
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0.858
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0.685
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0.760
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0.735
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0.745
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0.985
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0.829
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12.680.783
0.928
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0.608
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0.743
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0.860
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0.858
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0.966
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0.836
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0.546
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0.942
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0.684
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0.760
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0.826
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0.893
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0.683
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0.747
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0.755
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0.899
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0.804
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0.752
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0.986
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0.809
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13.120.782
0.976
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0.630
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0.815
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0.895
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0.932
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0.748
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0.732
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0.706
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0.994
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0.850
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0.892
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0.743
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0.855
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0.624
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0.890
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0.860
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0.827
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0.790
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0.628
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0.845
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0.684
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0.846
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0.693
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0.654
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0.980
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0.788
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17.270.749
0.863
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0.662
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0.740
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0.857
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0.819
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0.604
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0.870
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0.806
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0.929
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0.642
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0.725
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0.839
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0.630
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0.441
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0.907
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0.646
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0.701
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0.779
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0.836
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0.686
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0.648
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0.907
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0.782
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0.712
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0.683
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0.972
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0.797
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17.490.745
0.900
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0.602
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0.739
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0.861
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0.718
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0.769
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0.635
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0.927
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0.733
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0.797
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0.603
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0.561
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0.903
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0.783
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0.922
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0.998
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0.757
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0.646
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0.704
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0.853
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0.628
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0.438
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0.860
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0.561
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0.772
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0.690
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0.758
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0.596
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0.804
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0.636
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0.652
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0.894
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0.760
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0.735
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0.665
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0.955
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0.759
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17.850.741
0.851
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0.660
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0.735
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0.880
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0.711
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0.789
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0.515
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0.848
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0.701
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0.802
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0.588
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0.577
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0.885
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0.805
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0.931
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0.999
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0.792
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0.644
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0.682
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0.845
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0.625
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0.347
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0.898
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0.648
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0.554
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0.686
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0.685
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0.771
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0.621
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0.996
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0.823
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0.654
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0.666
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0.683
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0.663
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0.906
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0.748
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0.697
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0.687
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0.973
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0.804
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19.390.730
0.836
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0.690
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0.714
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0.849
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0.696
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0.764
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0.479
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0.834
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0.691
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0.750
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0.582
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0.561
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0.886
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0.793
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0.932
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0.995
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0.758
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0.645
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0.625
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0.846
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0.625
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0.467
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0.842
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0.673
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0.541
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0.737
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0.669
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0.753
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0.573
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0.993
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0.829
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0.647
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0.650
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0.634
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0.661
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0.872
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0.743
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0.720
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0.661
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0.956
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0.751
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19.200.726
0.884
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0.572
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0.668
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0.858
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0.703
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0.777
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0.551
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0.884
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0.728
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0.761
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0.557
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0.568
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0.879
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0.783
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0.908
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0.999
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0.734
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0.609
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0.653
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0.846
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0.663
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0.488
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0.861
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0.663
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0.474
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0.657
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0.670
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0.755
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0.596
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0.995
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0.821
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0.605
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0.648
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0.624
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0.640
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0.880
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0.751
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0.726
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0.661
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0.941
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0.741
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